This is what Theron has to say about it. It echoes what a lot of women her age say about dating:

“I’m in a place in my life where you have to come with a lot of game,” she told Barrymore. “Not the kind of game that we think of, the kind of game where my life is really good so you better be able to bring that and maybe better because I just won’t accept anything less.” She added, “I can honestly say this, on my life, I don’t feel lonely.”

“My life right now just doesn’t allow a lot of room for something like that to happen,” she continued. “But in saying that, there’s not this thing that drives me [to have a romantic relationship]. I enjoy being set up on dates but I don’t know if I’ll ever be able to live with somebody again. To be totally frank, they might have to buy the house next to me. I don’t know if I’m going to be able to deal with that ever again, I’m too old for that shit.”

https://graziamagazine.com/articles/charlize-theron-on-being-single-dating/#:~:text=%E2%80%9CMy%20life%20right%20now%20just,to%20live%20with%20somebody%20again.